American Board of Surgery Qualifying Exam (ABS QE) Practice Test

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What type of neoplasm is characterized as a common soft tissue sarcoma among adults?

Synovial sarcoma
Malignant fibrous histiocytoma
Pleomorphic sarcoma
Desmoid tumor

The correct answer is: Malignant fibrous histiocytoma

Malignant fibrous histiocytoma (MFH) is recognized as one of the most common soft tissue sarcomas in adults. It typically arises in deep soft tissues, particularly in the extremities and retroperitoneum, and is often seen in middle-aged individuals. MFH is characterized by its pleomorphic histological appearance, which includes a diverse mix of fibroblasts and histiocyte-like cells. The neoplasm is notable for its aggressive behavior and potential for local recurrence, thereby making it a significant entity in clinical and pathological discussions related to soft tissue sarcomas. While other types of sarcomas, such as synovial sarcoma, pleomorphic sarcoma, and desmoid tumors, do occur, MFH remains prominently recognized in clinical practice and literature, having been frequently cited in cases of soft tissue malignancies. Understanding the features and behavior of MFH is crucial for diagnosis, management, and prognosis in patients presenting with soft tissue masses.